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CVE-2025-27578: Use After Free Vulnerability in Pixmeo OsiriX MD

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Overview

This report discusses a significant cybersecurity vulnerability identified as CVE-2025-27578, primarily affecting Pixmeo OsiriX MD, a popular medical imaging software. This vulnerability is of critical importance due to its potential to cause system compromise and data leakage, leading to severe damage to both system integrity and confidentiality.

Vulnerability Summary

CVE ID: CVE-2025-27578
Severity: High (CVSS: 7.5)
Attack Vector: Network
Privileges Required: None
User Interaction: Required
Impact: System compromise or data leakage

Affected Products

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Product | Affected Versions

Pixmeo OsiriX MD | All versions prior to the patched version

How the Exploit Works

The vulnerability lies in the management of DICOM files, a standard for transmitting, storing, retrieving, and sharing medical images. An attacker can craft a malicious DICOM file and upload it to the affected system. The system, due to the use after free vulnerability, could then experience memory corruption, causing a denial-of-service condition.

Conceptual Example Code

Here is a conceptual example of how the vulnerability might be exploited. This example merely illustrates the exploit and does not contain actual malicious code.

POST /upload/dicom HTTP/1.1
Host: target.example.com
Content-Type: application/dicom
{ "dicom_file": "BASE64_ENCODED_MALICIOUS_DICOM_FILE_CONTENTS" }

In this example, the attacker sends a POST request to upload a crafted DICOM file. The malicious content within the DICOM file would trigger the use after free vulnerability, potentially leading to system compromise or data leakage.

Mitigation Guidance

Users are advised to apply the vendor-provided patch immediately to mitigate the vulnerability. If the patch cannot be applied immediately, the use of a Web Application Firewall (WAF) or Intrusion Detection System (IDS) can provide temporary mitigation. However, these are not long-term solutions and the patch should be applied as soon as possible to effectively secure the system.

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Disclaimer:

The information and code presented in this article are provided for educational and defensive cybersecurity purposes only. Any conceptual or pseudocode examples are simplified representations intended to raise awareness and promote secure development and system configuration practices.

Do not use this information to attempt unauthorized access or exploit vulnerabilities on systems that you do not own or have explicit permission to test.

Ameeba and its authors do not endorse or condone malicious behavior and are not responsible for misuse of the content. Always follow ethical hacking guidelines, responsible disclosure practices, and local laws.
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